Chien-Huang Lin Selected Research

denbinobin

1/2013	Denbinobin induces human glioblastoma multiforme cell apoptosis through the IKKα-Akt-FKHR signaling cascade.
5/2009	Apoptosis signal-regulating kinase 1 mediates denbinobin-induced apoptosis in human lung adenocarcinoma cells.
2/2008	Denbinobin induces apoptosis in human lung adenocarcinoma cells via Akt inactivation, Bad activation, and mitochondrial dysfunction.

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Chien-Huang Lin Research Topics

Disease

19	Neoplasms (Cancer) 01/2022 - 01/2002
11	Fibrosis (Cirrhosis) 10/2021 - 08/2013
7	Pneumonia (Pneumonitis) 08/2021 - 05/2013
7	Pulmonary Fibrosis (Fibrosing Alveolitis) 03/2019 - 08/2013
6	Hypoxia (Hypoxemia) 10/2021 - 05/2012
6	Asthma (Bronchial Asthma) 10/2021 - 03/2003
6	Mouth Neoplasms (Oral Cancer) 01/2015 - 01/2012
5	Thrombosis (Thrombus) 11/2015 - 04/2003
4	Colonic Neoplasms (Colon Cancer) 04/2016 - 08/2003
4	Squamous Cell Carcinoma of Head and Neck 01/2013 - 01/2012
3	Adenocarcinoma of Lung 01/2022 - 02/2008
3	Alzheimer Disease (Alzheimer's Disease) 07/2021 - 05/2007
2	Inflammation (Inflammations) 01/2022 - 04/2016
2	Infections 08/2014 - 01/2013
2	Hepatocellular Carcinoma (Hepatoma) 05/2014 - 09/2011
2	Sepsis (Septicemia) 03/2014 - 01/2004
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2014 - 10/2013
2	Glioblastoma (Glioblastoma Multiforme) 01/2013 - 10/2012
2	Carcinogenesis 01/2013 - 02/2012
2	Carcinoma (Carcinomatosis) 01/2012 - 04/2002
2	Glioma (Gliomas) 01/2012 - 05/2011
2	Neoplasm Metastasis (Metastasis) 12/2011 - 05/2011
2	Vascular Diseases (Vascular Disease) 12/2011 - 04/2006
2	Mitochondrial Diseases (Mitochondrial Disease) 03/2010 - 02/2008
1	Body Weight (Weight, Body) 01/2022
1	Emphysema 01/2022
1	Lung Neoplasms (Lung Cancer) 01/2022
1	Chronic Obstructive Pulmonary Disease (COPD) 02/2020
1	Idiopathic Pulmonary Fibrosis 01/2016

Drug/Important Bio-Agent (IBA)

13	Connective Tissue Growth FactorIBA 10/2021 - 01/2011
12	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2002
8	Thrombin FDA Link 08/2021 - 05/2013
6	Histone Deacetylases (Histone Deacetylase)IBA 01/2022 - 05/2011
5	Small Interfering RNA (siRNA)IBA 10/2021 - 10/2013
4	Histone Deacetylase InhibitorsIBA 01/2022 - 05/2011
4	Metalloproteases (Metalloproteinases)IBA 08/2021 - 01/2017
4	DisintegrinsIBA 08/2021 - 01/2017
4	Environmental CarcinogensIBA 01/2015 - 01/2012
3	RNA (Ribonucleic Acid)IBA 10/2021 - 01/2017
3	Coenzyme A (CoA)IBA 08/2021 - 08/2013
3	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2021 - 01/2016
3	Interleukin-8 (Interleukin 8)IBA 02/2020 - 08/2014
3	InterleukinsIBA 07/2017 - 04/2012
3	ChemokinesIBA 11/2015 - 01/2013
3	denbinobinIBA 01/2013 - 02/2008
3	theasinensin AIBA 02/2012 - 05/2011
3	Free RadicalsIBA 04/2006 - 08/2002
2	Pancreatic Elastase (Elastase)IBA 01/2022 - 11/2003
2	OvalbuminIBA 08/2021 - 05/2021
2	U 0126 (UO 126)IBA 01/2021 - 01/2016
2	CurcuminIBA 01/2021 - 03/2019
2	Phosphotransferases (Kinase)IBA 03/2019 - 01/2017
2	LuciferasesIBA 01/2017 - 01/2016
2	Serine Proteases (Serine Protease)IBA 11/2015 - 01/2014
2	Vascular Endothelial Growth Factor CIBA 05/2014 - 01/2013
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2014 - 01/2014
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2014 - 01/2012
2	Caspase 3 (Caspase-3)IBA 10/2013 - 02/2008
2	Cadherins (E-Cadherin)IBA 03/2012 - 09/2011
2	trichostatin A (A 300)IBA 02/2012 - 05/2011
2	DNA (Deoxyribonucleic Acid)IBA 03/2010 - 01/2002
2	Cyclin-Dependent Kinase 4IBA 08/2002 - 04/2002
2	Cyclin D3IBA 08/2002 - 04/2002
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2022
1	3- (1- benzenesulfonyl- 2,3- dihydro- 1H- indol- 5- yl)- N- hydroxyacrylamideIBA 01/2022
1	ErbB Receptors (EGF Receptor)IBA 01/2022
1	Protein CIBA 01/2022
1	Surface-Active Agents (Surfactants)IBA 01/2022
1	Sirtuin 1IBA 01/2022
1	fibrin fragment D (D-dimer)IBA 01/2022
1	Tyrosine Kinase InhibitorsIBA 01/2022
1	AfatinibIBA 01/2022
1	Gefitinib (Iressa)FDA Link 01/2022
1	osimertinibIBA 01/2022
1	IntegrinsIBA 10/2021
1	Fibronectins (Fibronectin)IBA 10/2021
1	Extracellular Matrix ProteinsIBA 10/2021
1	Messenger RNA (mRNA)IBA 01/2021
1	Endothelin-1 (Endothelin 1)IBA 03/2019
1	LigandsIBA 07/2017
1	CXC ChemokinesIBA 07/2017
1	CCAAT-Enhancer-Binding ProteinsIBA 01/2017
1	S 6 (S-6)IBA 01/2017
1	Bleomycin (Blenoxane)FDA LinkGeneric 10/2016
1	MicroRNAs (MicroRNA)IBA 10/2016
1	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 04/2016
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 04/2016
1	TOR Serine-Threonine KinasesIBA 04/2016
1	Sirolimus (Rapamycin)FDA Link 04/2016
1	GhrelinIBA 04/2016
1	Ghrelin ReceptorsIBA 04/2016
1	ChromatinIBA 01/2016
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2016
1	MAP Kinase Kinase Kinase 1IBA 01/2016
1	2- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA 01/2016
1	CollagenIBA 01/2016
1	SB 203580IBA 01/2016
1	p38 Mitogen-Activated Protein KinasesIBA 01/2016
1	Melatonin Receptors (Melatonin Receptor)IBA 01/2015

Therapy/Procedure

3	Drug Therapy (Chemotherapy) 01/2012 - 04/2002